CCG 102487 ( CCG102487 )

产品货号. M14206 CAS No. 353787-50-5

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

CCG 102487
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

CCG 102487 is a CCG-2979 analog that reduces streptokinase (SK) activity with little inhibition of group A streptococcal (GAS) growth.
产品描述

CCG 102487 is a CCG-2979 analog that reduces streptokinase (SK) activity with little inhibition of group A streptococcal (GAS) growth; alters the transcript level for key GAS virulence genes, including multiple adhesins (fibronectin binding proteins, collagen-like surface protein, laminin-binding surface protein, and M protein), cytolytic toxins (streptolysins O and S), secreted extracellular proteases (Mac, C5a peptidase, and SpeB), streptodornase Sda1 (DNase), complement inhibitor protein, and streptokinase.
同义词

CCG102487
通路

GPCR/G Protein
靶点

Antibacterial
受体

Antibacterial
研究领域

——
适应症

——

CAS Number

353787-50-5
分子量

428.59
分子式

C27H28N2OS
纯度

>98% (HPLC)
溶解度

——
SMILES

C=CCN1C(=O)C2=C(C3=CC=CC=C3CC24CCCCC4)N=C1SCC5=CC=CC=C5
化学全称

2-benzylsulfanyl-3-prop-2-enylspiro[6H-benzo[h]quinazoline-5,1'-cyclohexane]-4-one

1. Sun H, et al. Proc Natl Acad Sci U S A. 2012 Feb 28;109(9):3469-74.

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